Pharmacokinetics and pharmacodynamics of the vasopeptidase inhibitor, omapatrilat in healthy subjects

AIMS: To determine the pharmacokinetics, pharmacodynamics and tolerability of omapatrilat, a vasopeptidase inhibitor, in healthy subjects. METHODS: The effects of oral omapatrilat were evaluated in healthy men in two double-blind, placebo-controlled, dose-escalation trials. In a single-dose study, s...

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Hlavní autoři: Liao, Wei-chi, Vesterqvist, Ole, Delaney, Carol, Jemal, Mohammed, Ferreira, Irene, Ford, Neville, Swanson, Brian, Uderman, Howard
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2003
Témata:
Pharmacokinetics and Pharmacodynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884361/
https://ncbi.nlm.nih.gov/pubmed/12968984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01888.x
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