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Integrated pharmacokinetics and pharmacodynamics of epoprostenol in healthy subjects

AIM: The aim of the study was to report the first thorough characterization of the pharmacokinetics (PK) and pharmacodynamics (PD) of epoprostenol in an integrated manner. METHOD: Twenty healthy male subjects received two formulations of i.v. epoprostenol, in a crossover design, in sequential infusi...

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Bibliografische gegevens
Hoofdauteurs: Nicolas, Laurent B, Krause, Andreas, Gutierrez, Marcelo M, Dingemanse, Jasper
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522811/
https://ncbi.nlm.nih.gov/pubmed/22515646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04301.x
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