Pharmacokinetics and pharmacodynamics of γ‐hydroxybutyrate in healthy subjects

AIMS: γ‐Hydroxybutyrate (GHB) is used as a treatment for narcolepsy and alcohol withdrawal and as a recreational substance. Nevertheless, there are limited data on the pharmacokinetics and pharmacokinetic‐pharmacodynamic relationships of GHB in humans. We characterized the pharmacokinetic profile an...

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發表在:Br J Clin Pharmacol
Main Authors: Liechti, Matthias E., Quednow, Boris B., Liakoni, Evangelia, Dornbierer, Dario, von Rotz, Robin, Gachet, Maria Salomé, Gertsch, Jürg, Seifritz, Erich, Bosch, Oliver G.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
主題:
Pharmacokinetic Dynamic Relationships
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834605/
https://ncbi.nlm.nih.gov/pubmed/26659543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12863
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