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Confronting Complexity in Late-Onset Alzheimer Disease: Application of Two-Stage Analysis Approach Addressing Heterogeneity and Epistasis

Common diseases with a genetic basis are likely to have a very complex etiology, in which the mapping between genotype and phenotype is far from straightforward. A new comprehensive statistical and computational strategy for identifying the missing link between genotype and phenotype has been propos...

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Détails bibliographiques
Auteurs principaux: Thornton-Wells, Tricia A., Moore, Jason H., Martin, Eden R., Pericak-Vance, Margaret A., Haines, Jonathan L.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804868/
https://ncbi.nlm.nih.gov/pubmed/18076107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20294
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