Genome-wide Association Study Implicates a Chromosome 12 Risk Locus for Late-Onset Alzheimer Disease

Only Apolipoprotein E polymorphisms have been consistently associated with the risk of late-onset Alzheimer disease (LOAD), but they represent only a minority of the underlying genetic effect. To identify additional LOAD risk loci, we performed a genome-wide association study (GWAS) on 492 LOAD case...

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Hlavní autoři: Beecham, Gary W., Martin, Eden R., Li, Yi-Ju, Slifer, Michael A., Gilbert, John R., Haines, Jonathan L., Pericak-Vance, Margaret A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Human Genetics 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668056/
https://ncbi.nlm.nih.gov/pubmed/19118814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.12.008
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