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CALHM1 polymorphism is not associated with late-onset Alzheimer Disease

Data suggests that the P86L polymorphism (rs2986017) in the calcium homeostasis modulator 1 (CALHM1) gene interferes with CALHM1 functionality, increases Aβ levels, and is associated with late-onset Alzheimer's disease (LOAD). Dreses-Werringloer et al (2008) demonstrate association with P86L an...

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Bibliografske podrobnosti
Main Authors: Beecham, GW, Schnetz-Boutaud, N, Haines, JL, Pericak-Vance, MA
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918418/
https://ncbi.nlm.nih.gov/pubmed/19472444
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