Dementia Revealed: Novel Chromosome 6 Locus for Late-Onset Alzheimer Disease Provides Genetic Evidence for Folate-Pathway Abnormalities

Genome-wide association studies (GWAS) of late-onset Alzheimer disease (LOAD) have consistently observed strong evidence of association with polymorphisms in APOE. However, until recently, variants at few other loci with statistically significant associations have replicated across studies. The pres...

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Detalhes bibliográficos
Main Authors: Naj, Adam C., Beecham, Gary W., Martin, Eden R., Gallins, Paul J., Powell, Eric H., Konidari, Ioanna, Whitehead, Patrice L., Cai, Guiqing, Haroutunian, Vahram, Scott, William K., Vance, Jeffery M., Slifer, Michael A., Gwirtsman, Harry E., Gilbert, John R., Haines, Jonathan L., Buxbaum, Joseph D., Pericak-Vance, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944795/
https://ncbi.nlm.nih.gov/pubmed/20885792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001130
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