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Confronting Complexity in Late-Onset Alzheimer Disease: Application of Two-Stage Analysis Approach Addressing Heterogeneity and Epistasis
Common diseases with a genetic basis are likely to have a very complex etiology, in which the mapping between genotype and phenotype is far from straightforward. A new comprehensive statistical and computational strategy for identifying the missing link between genotype and phenotype has been propos...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804868/ https://ncbi.nlm.nih.gov/pubmed/18076107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20294 |
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