Assessment of the genetic variance of late-onset Alzheimer’s disease

Alzheimer’s disease (AD) is a complex genetic disorder with no effective treatments. More than 20 common markers have been identified, which are associated with AD. Recently, several rare variants have been identified in APP, TREM2, and UNC5C that affect risk for AD. Despite the many successes, the...

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Publié dans:Neurobiol Aging
Auteurs principaux: Ridge, Perry G., Hoyt, Kaitlyn B., Boehme, Kevin, Mukherjee, Shubhabrata, Crane, Paul K., Haines, Jonathan L., Mayeux, Richard, Farrer, Lindsay A., Pericak-Vance, Margaret A., Schellenberg, Gerard D., Kauwe, John S.K.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948179/
https://ncbi.nlm.nih.gov/pubmed/27036079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.02.024
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