Assessment of the genetic variance of late-onset Alzheimer’s disease

Alzheimer’s disease (AD) is a complex genetic disorder with no effective treatments. More than 20 common markers have been identified, which are associated with AD. Recently, several rare variants have been identified in APP, TREM2, and UNC5C that affect risk for AD. Despite the many successes, the...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Ridge, Perry G., Hoyt, Kaitlyn B., Boehme, Kevin, Mukherjee, Shubhabrata, Crane, Paul K., Haines, Jonathan L., Mayeux, Richard, Farrer, Lindsay A., Pericak-Vance, Margaret A., Schellenberg, Gerard D., Kauwe, John S.K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948179/
https://ncbi.nlm.nih.gov/pubmed/27036079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.02.024
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