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Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management
BACKGROUND: Lynch syndrome (LS) is associated with a high risk for colorectal cancer (CRC) and extracolonic malignancies, such as endometrial carcinoma (EC). The risk is dependent of the affected mismatch repair gene. The aim of the present study was to calculate the cumulative risk of LS related ca...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804564/ https://ncbi.nlm.nih.gov/pubmed/20028567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-7-17 |
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