Heparan Sulfate 2-O-Sulfotransferase Is Required for Triglyceride-rich Lipoprotein Clearance

Hepatic clearance of triglyceride-rich lipoproteins depends on heparan sulfate and low density lipoprotein receptors expressed on the basal membrane of hepatocytes. Binding and uptake of the lipoproteins by way of heparan sulfate depends on the degree of sulfation of the chains based on accumulation...

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Bibliografiske detaljer
Main Authors: Stanford, Kristin I., Wang, Lianchun, Castagnola, Jan, Song, Danyin, Bishop, Joseph R., Brown, Jillian R., Lawrence, Roger, Bai, Xaiomei, Habuchi, Hiroko, Tanaka, Masakazu, Cardoso, Wellington V., Kimata, Koji, Esko, Jeffrey D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804175/
https://ncbi.nlm.nih.gov/pubmed/19889634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063701
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