Heparan Sulfate 2-O-Sulfotransferase Is Required for Triglyceride-rich Lipoprotein Clearance

Hepatic clearance of triglyceride-rich lipoproteins depends on heparan sulfate and low density lipoprotein receptors expressed on the basal membrane of hepatocytes. Binding and uptake of the lipoproteins by way of heparan sulfate depends on the degree of sulfation of the chains based on accumulation...

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Hlavní autoři: Stanford, Kristin I., Wang, Lianchun, Castagnola, Jan, Song, Danyin, Bishop, Joseph R., Brown, Jillian R., Lawrence, Roger, Bai, Xaiomei, Habuchi, Hiroko, Tanaka, Masakazu, Cardoso, Wellington V., Kimata, Koji, Esko, Jeffrey D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804175/
https://ncbi.nlm.nih.gov/pubmed/19889634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063701
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