Dynamics of trimethoprim bound to dihydrofolate reductase.

The conformation of a small molecule in its binding site on a protein is a major factor in the specificity of the interaction between them. In this paper, we report the use of 1H and 13C NMR spectroscopy to study the fluctuations in conformation of the anti-bacterial drug trimethoprim when it is bou...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Searle, M S, Forster, M J, Birdsall, B, Roberts, G C, Feeney, J, Cheung, H T, Kompis, I, Geddes, A J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1988
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC280304/
https://ncbi.nlm.nih.gov/pubmed/3131763
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