Dynamics of trimethoprim bound to dihydrofolate reductase.

The conformation of a small molecule in its binding site on a protein is a major factor in the specificity of the interaction between them. In this paper, we report the use of 1H and 13C NMR spectroscopy to study the fluctuations in conformation of the anti-bacterial drug trimethoprim when it is bou...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Searle, M S, Forster, M J, Birdsall, B, Roberts, G C, Feeney, J, Cheung, H T, Kompis, I, Geddes, A J
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC280304/
https://ncbi.nlm.nih.gov/pubmed/3131763
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki