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Synthetic mRNA Splicing Modulator Compounds with In Vivo Anti-tumor Activity
We report our progress on the development of new synthetic anti-cancer lead compounds that modulate the splicing of mRNA. We also report the synthesis evaluation of new biologically active ester and carbamate analogs. Further, we describe initial animal studies demonstrating the antitumor efficacy o...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801547/ https://ncbi.nlm.nih.gov/pubmed/19877647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901215m |
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