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Synthetic mRNA Splicing Modulator Compounds with In Vivo Anti-tumor Activity
We report our progress on the development of new synthetic anti-cancer lead compounds that modulate the splicing of mRNA. We also report the synthesis evaluation of new biologically active ester and carbamate analogs. Further, we describe initial animal studies demonstrating the antitumor efficacy o...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801547/ https://ncbi.nlm.nih.gov/pubmed/19877647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901215m |
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