Synthetic mRNA Splicing Modulator Compounds with In Vivo Anti-tumor Activity

We report our progress on the development of new synthetic anti-cancer lead compounds that modulate the splicing of mRNA. We also report the synthesis evaluation of new biologically active ester and carbamate analogs. Further, we describe initial animal studies demonstrating the antitumor efficacy o...

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Detaylı Bibliyografya
Asıl Yazarlar: Lagisetti, Chandraiah, Pourpak, Alan, Goronga, Tinopiwa, Jiang, Qin, Cui, Xiaoli, Hyle, Judith, Lahti, Jill, Morris, Stephan W., Webb, Thomas R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801547/
https://ncbi.nlm.nih.gov/pubmed/19877647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901215m
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