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MHC class II expressing thymocytes suppress invariant NKT cell development
NKT cells are positively selected on cortical thymocytes expressing the non-classical MHC class I CD1d molecules. However, it is less clear how NKT cells are negatively selected in the thymus. In this study, we investigated the role of MHC class II expression in NKT cell development. Transgenic mice...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801351/ https://ncbi.nlm.nih.gov/pubmed/18982019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2008.78 |
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