MHC class II expressing thymocytes suppress invariant NKT cell development

NKT cells are positively selected on cortical thymocytes expressing the non-classical MHC class I CD1d molecules. However, it is less clear how NKT cells are negatively selected in the thymus. In this study, we investigated the role of MHC class II expression in NKT cell development. Transgenic mice...

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Hlavní autoři: Li, Wei, Sofi, M. Hanief, Wei, Datsen G., Du, Wenjun, Gervay-Hague, Jacquelyn, Renukaradhya, Gourapura J., Brutkiewicz, Randy R., Chang, Cheong-Hee
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801351/
https://ncbi.nlm.nih.gov/pubmed/18982019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2008.78
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