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Statins Impair CD1d-Mediated Antigen Presentation Through Inhibition of Prenylation

Statins are widely used as cholesterol-lowering agents that also decrease inflammation, and target enzymes essential for prenylation, an important process in the activation and intracellular transport of proteins vital for a wide variety of cellular functions. Here, we report that statins impair a c...

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Detalhes bibliográficos
Main Authors: Khan, Masood A., Gallo, Richard M., Renukaradhya, Gourapura J., Du, Wenjun, Gervay-Hague, Jacquelyn, Brutkiewicz, Randy R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850571/
https://ncbi.nlm.nih.gov/pubmed/19342651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804311
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