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Type I NKT cells protect (and type II NKT cells suppress) the host's innate antitumor immune response to a B-cell lymphoma

Natural killer T (NKT) cells are a T-cell subpopulation known to possess immunoregulatory functions and recognize CD1d molecules. The majority of NKT cells express an invariant T-cell receptor (TCR) α chain rearrangement (Vα14Jα18 in mice; Vα24Jα18 in humans) and are called type I NKT cells; all oth...

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Detalhes bibliográficos
Main Authors: Renukaradhya, Gourapura J., Khan, Masood A., Vieira, Marcus, Du, Wenjun, Gervay-Hague, Jacquelyn, Brutkiewicz, Randy R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424159/
https://ncbi.nlm.nih.gov/pubmed/18417738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-092866
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