MHC class II expressing thymocytes suppress invariant NKT cell development

NKT cells are positively selected on cortical thymocytes expressing the non-classical MHC class I CD1d molecules. However, it is less clear how NKT cells are negatively selected in the thymus. In this study, we investigated the role of MHC class II expression in NKT cell development. Transgenic mice...

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Detalhes bibliográficos
Main Authors: Li, Wei, Sofi, M. Hanief, Wei, Datsen G., Du, Wenjun, Gervay-Hague, Jacquelyn, Renukaradhya, Gourapura J., Brutkiewicz, Randy R., Chang, Cheong-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801351/
https://ncbi.nlm.nih.gov/pubmed/18982019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2008.78
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