Vaccinia virus infection induces dendritic cell maturation but inhibits antigen presentation by MHC class II

Vaccinia virus (VV) infection is known to inhibit dendritic cells (DC) functions in vitro. Paradoxically, VV is also highly immunogenic and thus has been used as a vaccine. In the present study, we investigated the effects of an in vivo VV infection on DC function by focusing on early innate immunit...

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Autores principales: Yao, Yongxue, Li, Ping, Singh, Pratibha, Thiele, Allison T., Wilkes, David S., Renukaradhya, Gourapura J., Brutkiewicz, Randy R., Travers, Jeffrey B., Luker, Gary D., Hong, Soon-Cheol, Blum, Janice S., Chang, Cheong-Hee
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2100387/
https://ncbi.nlm.nih.gov/pubmed/17678637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2007.06.005
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