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Inherent Anti-amyloidogenic Activity of Human Immunoglobulin γ Heavy Chains
We have previously shown that a subpopulation of naturally occurring human IgGs were cross-reactive against conformational epitopes on pathologic aggregates of Aβ, a peptide that forms amyloid fibrils in the brains of patients with Alzheimer disease, inhibited amyloid fibril growth, and dissociated...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801233/ https://ncbi.nlm.nih.gov/pubmed/19889627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.044321 |
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