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Localization of a Conformational Epitope Common to Non-Native and Fibrillar Immunoglobulin Light Chains

Amyloid fibrils and partially unfolded intermediates may be distinguished serologically from native amyloidogenic precursor proteins or peptides. In this regard, we had previously reported that the IgG1 mAb 11-1F4, generated by immunizing mice with a thermally denatured variable region fragment of t...

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Detalhes bibliográficos
Main Authors: O'Nuallain, Brian, Allen, Amy, Kennel, Stephen J., Weiss, Deborah T., Solomon, Alan, Wall, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1832162/
https://ncbi.nlm.nih.gov/pubmed/17260953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0616605
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