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Conformational Abs recognizing a generic amyloid fibril epitope
Disease-related amyloid fibrils appear to share a common, but poorly understood, structure. We describe here the generation and preliminary characterization of two conformation-specific mAbs, WO1 and WO2, that bind to the amyloid fibril state of the Alzheimer's peptide Aβ(1–40) but not to its s...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122217/ https://ncbi.nlm.nih.gov/pubmed/11818542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022662599 |
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