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Phage Display and Peptide Mapping of an Immunoglobulin Light Chain Fibril-Related Conformational Epitope

Amyloid fibrils and partially unfolded intermediates can be distinguished serologically from native amyloidogenic precursor proteins or peptides. In this regard, we previously had reported that mAb 11-1F4, generated by immunizing mice with a thermally denatured variable domain (V(L)) fragment of the...

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Autors principals: O’Nuallain, Brian, Allen, Amy, Ataman, Demet, Weiss, Deborah T., Solomon, Alan, Wall, Jonathan S.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677975/
https://ncbi.nlm.nih.gov/pubmed/17944486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701255m
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