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Inhibition of pathologic immunoglobulin free light chain production by small interfering RNA molecules

OBJECTIVES: Morbidity and mortality occurring in patients with multiple myeloma, AL amyloidosis, and light chain deposition disease can result from the pathologic deposition of monoclonal Ig light chains (LCs) in kidneys and other organs. To reduce synthesis of such components, therapy for these dis...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Phipps, Jonathan E., Kestler, Daniel P., Foster, James S., Kennel, Stephen J., Donnell, Robert, Weiss, Deborah T., Solomon, Alan, Wall, Jonathan S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962681/
https://ncbi.nlm.nih.gov/pubmed/20637260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.07.001
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