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Localization of a Conformational Epitope Common to Non-Native and Fibrillar Immunoglobulin Light Chains

Amyloid fibrils and partially unfolded intermediates may be distinguished serologically from native amyloidogenic precursor proteins or peptides. In this regard, we had previously reported that the IgG1 mAb 11-1F4, generated by immunizing mice with a thermally denatured variable region fragment of t...

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Bibliografske podrobnosti
Main Authors: O'Nuallain, Brian, Allen, Amy, Kennel, Stephen J., Weiss, Deborah T., Solomon, Alan, Wall, Jonathan S.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1832162/
https://ncbi.nlm.nih.gov/pubmed/17260953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0616605
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