Age-Related Vascular Pathology in Transgenic Mice Expressing Presenilin 1-Associated Familial Alzheimer's Disease Mutations

Mutations in the presenilin 1 (PS1) gene are the most commonly recognized cause of familial Alzheimer's disease (FAD). Besides senile plaques, neurofibrillary tangles, and neuronal loss, Alzheimer's disease (AD) is also accompanied by vascular pathology. Here we describe an age-related vas...

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Autors principals: Gama Sosa, Miguel A., Gasperi, Rita De, Rocher, Anne B., Wang, Athena Ching-Jung, Janssen, William G.M., Flores, Tony, Perez, Gissel M., Schmeidler, James, Dickstein, Dara L., Hof, Patrick R., Elder, Gregory A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797896/
https://ncbi.nlm.nih.gov/pubmed/20008141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090482
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