Age-Related Vascular Pathology in Transgenic Mice Expressing Presenilin 1-Associated Familial Alzheimer's Disease Mutations

Mutations in the presenilin 1 (PS1) gene are the most commonly recognized cause of familial Alzheimer's disease (FAD). Besides senile plaques, neurofibrillary tangles, and neuronal loss, Alzheimer's disease (AD) is also accompanied by vascular pathology. Here we describe an age-related vas...

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Main Authors: Gama Sosa, Miguel A., Gasperi, Rita De, Rocher, Anne B., Wang, Athena Ching-Jung, Janssen, William G.M., Flores, Tony, Perez, Gissel M., Schmeidler, James, Dickstein, Dara L., Hof, Patrick R., Elder, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797896/
https://ncbi.nlm.nih.gov/pubmed/20008141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090482
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