Age-Related Vascular Pathology in Transgenic Mice Expressing Presenilin 1-Associated Familial Alzheimer's Disease Mutations

Mutations in the presenilin 1 (PS1) gene are the most commonly recognized cause of familial Alzheimer's disease (FAD). Besides senile plaques, neurofibrillary tangles, and neuronal loss, Alzheimer's disease (AD) is also accompanied by vascular pathology. Here we describe an age-related vas...

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Bibliografiska uppgifter
Huvudupphovsmän: Gama Sosa, Miguel A., Gasperi, Rita De, Rocher, Anne B., Wang, Athena Ching-Jung, Janssen, William G.M., Flores, Tony, Perez, Gissel M., Schmeidler, James, Dickstein, Dara L., Hof, Patrick R., Elder, Gregory A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2010
Ämnen:
Regular Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797896/
https://ncbi.nlm.nih.gov/pubmed/20008141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090482
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