Structural Biology of Human H3K9 Methyltransferases

SET domain methyltransferases deposit methyl marks on specific histone tail lysine residues and play a major role in epigenetic regulation of gene transcription. We solved the structures of the catalytic domains of GLP, G9a, Suv39H2 and PRDM2, four of the eight known human H3K9 methyltransferases in...

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Main Authors: Wu, Hong, Min, Jinrong, Lunin, Vladimir V., Antoshenko, Tatiana, Dombrovski, Ludmila, Zeng, Hong, Allali-Hassani, Abdellah, Campagna-Slater, Valérie, Vedadi, Masoud, Arrowsmith, Cheryl H., Plotnikov, Alexander N., Schapira, Matthieu
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797608/
https://ncbi.nlm.nih.gov/pubmed/20084102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008570
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