Structural Biology of Human H3K9 Methyltransferases

SET domain methyltransferases deposit methyl marks on specific histone tail lysine residues and play a major role in epigenetic regulation of gene transcription. We solved the structures of the catalytic domains of GLP, G9a, Suv39H2 and PRDM2, four of the eight known human H3K9 methyltransferases in...

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Detalhes bibliográficos
Main Authors: Wu, Hong, Min, Jinrong, Lunin, Vladimir V., Antoshenko, Tatiana, Dombrovski, Ludmila, Zeng, Hong, Allali-Hassani, Abdellah, Campagna-Slater, Valérie, Vedadi, Masoud, Arrowsmith, Cheryl H., Plotnikov, Alexander N., Schapira, Matthieu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797608/
https://ncbi.nlm.nih.gov/pubmed/20084102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008570
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