Structural Biology of Human H3K9 Methyltransferases

SET domain methyltransferases deposit methyl marks on specific histone tail lysine residues and play a major role in epigenetic regulation of gene transcription. We solved the structures of the catalytic domains of GLP, G9a, Suv39H2 and PRDM2, four of the eight known human H3K9 methyltransferases in...

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Hauptverfasser: Wu, Hong, Min, Jinrong, Lunin, Vladimir V., Antoshenko, Tatiana, Dombrovski, Ludmila, Zeng, Hong, Allali-Hassani, Abdellah, Campagna-Slater, Valérie, Vedadi, Masoud, Arrowsmith, Cheryl H., Plotnikov, Alexander N., Schapira, Matthieu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797608/
https://ncbi.nlm.nih.gov/pubmed/20084102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008570
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