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Competition Between Co(NH(3))(6)(3+) and Inner Sphere Mg(2+) Ions in the HDV Ribozyme

Divalent cations play critical structural and functional roles in many RNAs. While the hepatitis delta virus (HDV) ribozyme can undergo self-cleavage in the presence of molar concentrations of monovalent cations, divalent cations such as Mg(2+) are required for efficient catalysis under physiologica...

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Detalhes bibliográficos
Main Authors: Gong, Bo, Chen, Jui-Hui, Bevilacqua, Philip C., Golden, Barbara L., Carey, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795014/
https://ncbi.nlm.nih.gov/pubmed/19888753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901091v
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