Anti-apoptotic Molecule Bcl-2 Regulates the Differentiation, Activation, and Survival of Both Osteoblasts and Osteoclasts

The anti-apoptotic molecule Bcl-2 inhibits apoptosis by preventing cytochrome c release from mitochondria. Although several studies have indicated the importance of Bcl-2 in maintaining skeletal integrity, the detailed cellular and molecular mechanisms remain elusive. Bcl-2(−/−) mice are growth-reta...

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Dades bibliogràfiques
Autors principals: Nagase, Yuichi, Iwasawa, Mitsuyasu, Akiyama, Toru, Kadono, Yuho, Nakamura, Masaki, Oshima, Yasushi, Yasui, Tetsuro, Matsumoto, Takumi, Hirose, Jun, Nakamura, Hiroaki, Miyamoto, Takeshi, Bouillet, Philippe, Nakamura, Kozo, Tanaka, Sakae
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Molecular Basis of Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794780/
https://ncbi.nlm.nih.gov/pubmed/19846553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.016915
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