Pivotal Role of Bcl-2 Family Proteins in the Regulation of Chondrocyte Apoptosis

During endochondral ossification, chondrocytes undergo hypertrophic differentiation and die by apoptosis. The level of inorganic phosphate (P(i)) elevates at the site of cartilage mineralization, and when chondrocytes were treated with P(i), they underwent rapid apoptosis. Gene silencing of the proa...

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Autores principales: Oshima, Yasushi, Akiyama, Toru, Hikita, Atsuhiko, Iwasawa, Mitsuyasu, Nagase, Yuichi, Nakamura, Masaki, Wakeyama, Hidetoshi, Kawamura, Naohiro, Ikeda, Toshiyuki, Chung, Ung-il, Hennighausen, Lothar, Kawaguchi, Hiroshi, Nakamura, Kozo, Tanaka, Sakae
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Molecular Basis of Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546555/
https://ncbi.nlm.nih.gov/pubmed/18632667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800933200
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