In vitro and in vivo assays for osteoclast apoptosis

Mature osteoclasts, multinucleated giant cells responsible for bone resorption, are terminally differentiated cells with a short life span. Recently, we have demonstrated that osteoclast apoptosis is regulated by ERK activity and Bcl-2 family member Bim. In this paper, we summarize the methods we us...

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Bibliographic Details
Main Authors: Akiyama, Toru, Miyazaki, Tsuyoshi, Bouillet, Phillippe, Nakamura, Kozo, Strasser, Andreas, Tanaka, Sakae
Format: Artigo
Language:Inglês
Published: Biological Procedures Online 2005
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190379/
https://ncbi.nlm.nih.gov/pubmed/16136224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1251/bpo105
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