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Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein
The cAMP receptor protein (CRP) from Mycobacterium tuberculosis is a cAMP-responsive global transcriptional regulator, responsible for the regulation of a multitude of diverse proteins. We have determined the crystal structures of the CRP·cAMP and CRP·N(6)-cAMP derivative-bound forms of the enzyme t...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794773/ https://ncbi.nlm.nih.gov/pubmed/19740754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041343 |
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