cAMP is an allosteric modulator of DNA-binding specificity in the cAMP receptor protein from Mycobacterium tuberculosis

Allosteric proteins with multiple subunits and ligand-binding sites are central in regulating biological signals. The cAMP receptor protein from Mycobacterium tuberculosis (CRP(MTB)) is a global regulator of transcription composed of two identical subunits, each one harboring structurally conserved...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gárate, Fernanda, Dokas, Stephen, Lanfranco, Maria Fe, Canavan, Clare, Wang, Irina, Correia, John J., Maillard, Rodrigo A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026907/
https://ncbi.nlm.nih.gov/pubmed/33640453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100480
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