The N-terminal Capping Propensities of the D-helix Modulate the Allosteric Activation of the Escherichia coli cAMP Receptor Protein

Transduction of biological signals at the molecular level involves the activation and/or inhibition of allosteric proteins. In the transcription factor cAMP receptor protein (CRP) from Escherichia coli, the allosteric activation, or apo-holo transition, involves rigid body motions of domains and str...

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Bibliographic Details
Main Authors: Yu, Shaoning, Maillard, Rodrigo A., Gribenko, Alexey V., Lee, J. Ching
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501046/
https://ncbi.nlm.nih.gov/pubmed/23035121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.404806
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