Učitavanje...
Molecular Modeling of the Misfolded Insulin Subunit and Amyloid Fibril
Insulin, a small hormone protein comprising 51 residues in two disulfide-linked polypeptide chains, adopts a predominantly α-helical conformation in its native state. It readily undergoes protein misfolding and aggregates into amyloid fibrils under a variety of conditions. Insulin is a unique model...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2793351/ https://ncbi.nlm.nih.gov/pubmed/20006956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.042 |
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