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Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3

The kinase domain of human epidermal growth factor receptor (HER) 3/ErbB3, a member of the EGF receptor (EGFR) family, lacks several residues that are critical for catalysis. Because catalytic activity in EGFR family members is switched on by an allosteric interaction between kinase domains in an as...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jura, Natalia, Shan, Yibing, Cao, Xiaoxian, Shaw, David E., Kuriyan, John
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791034/
https://ncbi.nlm.nih.gov/pubmed/20007378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912101106
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