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Catalytic control in the EGF Receptor and its connection to general kinase regulatory mechanisms

In contrast to the active conformations of protein kinases, which are essentially the same for all kinases, inactive kinase conformations are structurally diverse. Some inactive conformations are, however, observed repeatedly in different kinases, perhaps reflecting an important role in catalysis. I...

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Detalhes bibliográficos
Main Authors: Jura, Natalia, Zhang, Xuewu, Endres, Nicholas F., Seeliger, Markus A., Schindler, Thomas, Kuriyan, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175429/
https://ncbi.nlm.nih.gov/pubmed/21474065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.004
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