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Regulation of the catalytic activity of the EGF receptor

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase involved in cell growth that is often misregulated in cancer. Several recent studies highlight the unique structural mechanisms involved in its regulation. Some elucidate the important role that the juxtamembrane segment and t...

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Detalhes bibliográficos
Main Authors: Endres, Nicholas F., Engel, Kate, Das, Rahul, Kovacs, Erika, Kuriyan, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232302/
https://ncbi.nlm.nih.gov/pubmed/21868214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2011.07.007
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