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Architecture and membrane interactions of the EGF receptor
Dimerization-driven activation of the intracellular kinase domains of the epidermal growth factor receptor (EGFR) upon extracellular ligand binding is a key step in cellular pathways regulating proliferation, migration, and differentiation. Inactive EGFR can exist as both monomers and dimers, sugges...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3680629/ https://ncbi.nlm.nih.gov/pubmed/23374350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.030 |
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