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Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3
The kinase domain of human epidermal growth factor receptor (HER) 3/ErbB3, a member of the EGF receptor (EGFR) family, lacks several residues that are critical for catalysis. Because catalytic activity in EGFR family members is switched on by an allosteric interaction between kinase domains in an as...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2791034/ https://ncbi.nlm.nih.gov/pubmed/20007378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912101106 |
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