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Design Principles for Ligand-Sensing, Conformation-Switching Ribozymes
Nucleic acid sensor elements are proving increasingly useful in biotechnology and biomedical applications. A number of ligand-sensing, conformational-switching ribozymes (also known as allosteric ribozymes or aptazymes) have been generated by some combination of directed evolution or rational design...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2009
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789328/ https://ncbi.nlm.nih.gov/pubmed/20041206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000620 |
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