Loading...

Design and optimization of effector-activated ribozyme ligases

A selected ribozyme ligase, L1, has been engineered to respond to small organic effectors. Residues important for ribozyme catalysis were mapped to a compact core structure. Aptamers that bound adenosine and theophylline were appended to the core structure, and the resultant aptazymes proved to be r...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Robertson, Michael P., Ellington, Andrew D.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC102822/
https://ncbi.nlm.nih.gov/pubmed/10734194
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!